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20 Dec 2019, 8:49 am
On January 22, the justices added another blockbuster case to their docket, this time for the 2019-2020 term: a challenge to a New York City regulation that banned the transport of guns anywhere outside the city limits, including to shooting ranges for target practice and vacation homes. [read post]
13 Apr 2024, 3:33 pm
Prelude to Litigation Phenylpropanolamine (PPA) was a widely used direct α-adrenergic agonist used as a medication to control cold symptoms and to suppress appetite for weight loss.[1] In 1972, an over-the-counter (OTC) Advisory Review Panel considered the safety and efficacy of PPA-containing nasal decongestant medications, leading, in 1976, to a recommendation that the agency label these medications as “generally recognized as safe and effective. [read post]
19 Mar 2022, 2:09 pm
The regulatory approach to such compounds can be based on the identification of a No-Observed Effect Level (NOEL) and use of uncertainty factors (see ICH Q3C(R5), Ref. 7) to calculate a permissible daily exposure (PDE) when data are available. [read post]
3 Nov 2011, 9:12 pm
Fairness in Numbers: A Comment on AT&T v. [read post]
