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12 Dec 2021, 2:22 pm
In assessing an association for causality, the starting point is “an association between two variables, perfectly clear-cut and beyond what we would care to attribute to the play of chance. [read post]
13 Apr 2024, 3:33 pm
Prelude to Litigation Phenylpropanolamine (PPA) was a widely used direct α-adrenergic agonist used as a medication to control cold symptoms and to suppress appetite for weight loss.[1] In 1972, an over-the-counter (OTC) Advisory Review Panel considered the safety and efficacy of PPA-containing nasal decongestant medications, leading, in 1976, to a recommendation that the agency label these medications as “generally recognized as safe and effective. [read post]